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MLB Picks · 2026-05-22

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2W 3L 5 graded picks
Pick of the Day · 2026-05-22
Cleveland Guardians @ Philadelphia Phillies
Cleveland Guardians
Line: +154 Edge: +17.1% Slight edge 1-0 W

Cleveland Guardians (away) - season-to-date numbers show a slight lean over Philadelphia Phillies. Win probability: 56%. Early-season: win % held closer to a toss-up until samples grow. Line +154 → edge +17.1% vs implied. Calibrated vs 280 graded results.

PICK #2 Pittsburgh Pirates Pittsburgh Pirates @ Toronto Blue Jays
+136 +12.0% Slight edge L

Pittsburgh Pirates (away) - season-to-date numbers show a slight lean over Toronto Blue Jays. Win probability: 54%. Early-season: win % held closer to a toss-up until samples grow. Line +136 → edge +12.0% vs implied. Calibrated vs 280 graded results.

PICK #3 Chicago Cubs Houston Astros @ Chicago Cubs
-142 +6.4% Slight edge L

Chicago Cubs (home) - season-to-date numbers show a slight lean over Houston Astros. Win probability: 65%. Early-season: win % held closer to a toss-up until samples grow. Line -142 → edge +6.4% vs implied. Calibrated vs 280 graded results.

PICK #4 Detroit Tigers Detroit Tigers @ Baltimore Orioles
+112 +5.0% Slight edge L

Detroit Tigers (away) - season-to-date numbers show a slight lean over Baltimore Orioles. Win probability: 52%. Early-season: win % held closer to a toss-up until samples grow. Line +112 → edge +5.0% vs implied. Calibrated vs 280 graded results.

PICK #5 Chicago White Sox Chicago White Sox @ San Francisco Giants
-108 +4.3% Slight edge W

Chicago White Sox (away) - season-to-date numbers show a slight lean over San Francisco Giants. Win probability: 56%. Early-season: win % held closer to a toss-up until samples grow. Line -108 → edge +4.3% vs implied. Calibrated vs 280 graded results.

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