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MLB picks for Friday, May 22, 2026

The Daily Picks Free model card. Graded at the posted line, flat 1u. Today’s MLB card · MLB record

2W 3L 5 graded picks

Pick of the Day · Fri, May 22

Houston Astros @ Chicago Cubs

Chicago Cubs

Line: -142 Slight edge 4-2 Final L

Chicago Cubs (home) - season-to-date numbers show a slight lean over Houston Astros. Early-season: win % held closer to a toss-up until samples grow. Calibrated vs 672 graded results.

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PICK #2 Cleveland Guardians Cleveland Guardians @ Philadelphia Phillies

+154 Slight edge W

Cleveland Guardians (away) - season-to-date numbers show a slight lean over Philadelphia Phillies. Early-season: win % held closer to a toss-up until samples grow. Calibrated vs 672 graded results.

PICK #3 Pittsburgh Pirates Pittsburgh Pirates @ Toronto Blue Jays

+136 Slight edge L

Pittsburgh Pirates (away) - season-to-date numbers show a slight lean over Toronto Blue Jays. Early-season: win % held closer to a toss-up until samples grow. Calibrated vs 672 graded results.

PICK #4 Detroit Tigers Detroit Tigers @ Baltimore Orioles

+112 Slight edge L

Detroit Tigers (away) - season-to-date numbers show a slight lean over Baltimore Orioles. Early-season: win % held closer to a toss-up until samples grow. Calibrated vs 672 graded results.

PICK #5 Chicago White Sox Chicago White Sox @ San Francisco Giants

-108 Slight edge W

Chicago White Sox (away) - season-to-date numbers show a slight lean over San Francisco Giants. Early-season: win % held closer to a toss-up until samples grow. Calibrated vs 672 graded results.

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